That’s not usually the problem. Usually you can generally do this on any distro, even ones that have a higher level of integration with their DE.
The problem is more likely to be issues caused by overlapping configurations and base libraries that can cause weird issues if they aren’t swapped out or kept default. If they aren’t default and are managed by the package manager, usually the package manager will mark it as modified and often won’t touch it unless you purge the configurations. Some will ask and some will straight up nuke em.
That’s not usually the problem. Usually you can generally do this on any distro, even ones that have a higher level of integration with their DE.
The problem is more likely to be issues caused by overlapping configurations and base libraries that can cause weird issues if they aren’t swapped out or kept default. If they aren’t default and are managed by the package manager, usually the package manager will mark it as modified and often won’t touch it unless you purge the configurations. Some will ask and some will straight up nuke em.