Would you want it to be like the Fallout show with a new story, or would you want it to follow one of the games that we already have. If you want a new story and/or setting, where and when would you like it? Me personally would like to see it take place in Elswyr
An Imperial boat ride into Black Marsh prob second era the coincidence w/ the Crimson plague.
It could drastically expand and clarify the Black Marsh lore without removing all of the mystique like setting a game there would because TV unlike an open world RPG limits what is shown to the viewer.
That time frame + setting would also give the show a lot of creative license because it has a bunch of races that got wiped out by the plague and have very little established lore.