Firefox uses xdg-mime or xdg portals, depending on the configuration of the package. If you are using it as a flatpak, it will use portals.
Apps using portals will use the file picker your portal provides. This will usually be either the GNOME or Plasma file picker. Note that this file picker is separate from your default file manager.
Until some app doesn’t care about xdg-mime. At least I had some issues with firefox a while ago.
Firefox uses xdg-mime or xdg portals, depending on the configuration of the package. If you are using it as a flatpak, it will use portals.
Apps using portals will use the file picker your portal provides. This will usually be either the GNOME or Plasma file picker. Note that this file picker is separate from your default file manager.